Manchester United's Dutch striker Robin van Persie (2nd R) is substituted by Scottish manager Alex Ferguson (R) after picking up an injury during the English Premier League football match between Queens Park Rangers and Manchester United at Loftus Road in London on February 23, 2012. AFP PHOTO/OLLY GREENWOOD RESTRICTED TO EDITORIAL USE. No use with unauthorized audio, video, data, fixture lists, club/league logos or ?live? services. Online in-match use limited to 45 images, no video emulation. No use in betting, games or single club/league/player publications