Jaguares remain three points adrift at the foot of the Clausura after suffering a 2-0 defeat at mid-table Atlas.
Ricardo Jimenez and substitute Jahir Barraza sealed the win for Atlas as Jaguares failed to capitalise on Necaxa's defeat to Unam Pumas.
Ten-man Cruz Azul battled to a 1-1 draw with Guadalajara despite having Horacio Cervantes dismissed in the 40th minute.
They fell behind to Marco Jhonfai Fabian's goal on the stroke of half-time, but Emanuel Villa levelled with nine minutes to play to secure a share of the spoils.
Carlos Bueno's last-minute equaliser gave Queretaro a 1-1 draw with Pachuca after the visitors had taken the lead through Herculez Gomez.
Wilmer Aguirre's hat-trick saw San Luis win 3-1 at Santos Laguna. Aguirre had put the game beyond doubt before the hosts scored through Juan Rodriguez's penalty, which saw Christian Sanchez red-carded for giving away the spot-kick.
Felix Borja's goal gave Puebla an early lead at Monterrey, but Jesus Zavala equalised in the 1-1 draw.
