Two derby battles dominate the Premier League this weekend. League leaders Chelsea, fresh from their 1-0 UEFA Champions League success over Porto, host rivals Tottenham on Sunday, who themselves have enjoyed an excellent start to the new season.

And Manchester will be rocking, also on Sunday, when big spenders City travel to Old Trafford, the first time the two sides have met since Mark Hughes was let loose with the Eastlands cheque book.

In London, Carlo Ancelotti will be pitting his wits against Harry Redknapp, who will be looking at bouncing straight back from the 3-1 defeat at White Hart Lane to reigning champions United.

Defender Sebastian Bassong is also looking for a positive response to the defeat. The summer signing from Newcastle said: "We have to show a good reaction at Stamford Bridge, we have a good squad, a good spirit and that's what we intend to do."

Off the field Chelsea have announced Ron Gourlay as the successor to Peter Kenyon, who announced this week he was to stand down as chief executive. Gourlay said: "It is a huge honour to be offered the chance to lead Chelsea."

Chelsea have been overtaken by Manchester City as the Premier League's big spenders and Hughes will be returning to his old stomping ground with a new-look side which many believe could break into the top four.

City, like Chelsea, have still to drop a point in the Premier League but waiting in anticipation will be their old foes, who beat Besiktas in Istanbul in midweek thanks to a Paul Scholes goal. Scholes is suspended for the derby after being sent off against Spurs last week.

Defender Jonny Evans said: "We all know about the big rivalry between United and City and it's always nice to get the upper hand on them. They have put themselves up there now. It's a long season but fair play to them because they've got off to a good start."

City will be without striker Emmanuel Adebayor after he was banned for three matches for stamping on Robin van Persie in the match against Arsenal last weekend. Sunday's two other games see Everton host Blackburn and Fulham travel to Wolves.

Arsenal have had the least time to recover of the four English teams who were taking part, and winning, in the Champions League. After their thrilling 3-2 victory over Standard Liege on Wednesday evening, Wigan are the visitors for the 3pm Saturday match.

Boss Arsene Wenger has a number of injury worries and is without Theo Walcott (back), Samir Nasri (leg), Lukasz Fabianski, Johan Djourou (both knee) and Carlos Vela (ankle). But Andrey Arshavin (groin) has an outside chance of making the squad for Saturday.

Wenger said: "Robin van Persie is the most likely to come back [for Saturday]. Denilson looks to be out for a few weeks with a back problem. There is a 10% chance for Arshavin."

Wigan manager Roberto Martinez is keen to copy the top sides like Arsenal. He said: "They are arrogant on the ball and that is something I like in my teams."

Like Wigan, Liverpool also travel from the north to the capital. The Reds will be hoping for an improved performance after their 1-0 victory over Debrecen in their opening Champions League match, but boss Rafael Benitez knows that with victories comes confidence.

He said: "It was important just to win and now we can approach the next game with more confidence. We are winning games in a row now so hopefully confidence in the dressing room will be higher."

In the early Saturday kick-off Sunderland travel to Burnley. And the remaining three games are all in the traditional 3pm Saturday afternoon slot - Aston Villa host Portsmouth, Stoke travel to Bolton and Hull are at home to Birmingham.