Lazio await bids for unsettled trio
The three players have each expressed their desire to leave the Rome outfit this summer, and Lotito is prepared to grant their requests on the proviso interested parties meet the club's valuations.
"For the time being they remain Lazio players," said Lotito. "They want to leave and they will have to take responsibility.
"I have agreed with them the terms for their exits. They must bring in offers from clubs that pay those figures in order to be released from their contracts.
"I am surprised that they have not shown any attachment to Lazio but I will not wait for eternity. We have certain aims and the coach needs to work with a definite roster."
Argentinian midfielder Ledesma and Italian fullback De Silvestri are reported targets of Juventus, while Pandev has been strongly linked with a move to Zenit.
But Lotito has denied receiving a bid from the Russian outfit for the FYR Macedonia forward. "I have had no proposals from Zenit," he said.
"We offered Pandev a contract extension with a high salary but if he thinks that he can earn €3m (per season), we are not the club that can make him happy."