In-form Liverpool striker Daniel Sturridge and Cardiff City centre-back Steven Caulker have been ruled out of England's FIFA World Cup™ qualifier against Moldova on Friday due to injury, the Football Association (FA) announced on Thursday.
Sturridge, 24, has scored the only goal in three successive games to send Liverpool to the top of the English Premier League, but he aggravated a groin injury in Sunday's 1-0 win over Manchester United.
However, England are hopeful he will be able to join up with the squad for Tuesday's trip to Ukraine in European qualifying Group H.
"The squad departed St George's Park on Thursday afternoon ahead of the World Cup qualifier at Wembley, but the Liverpool forward will return to his club with the intention of joining the England squad again at the weekend and travelling to Ukraine."
Caulker, 21, turned his ankle in training, but he had not been expected to start the game against Moldova.
"It's not a serious matter, but it will keep him out of the game tomorrow night," Hodgson said. "It won't keep him out of the Ukraine game. He's expected to do some running tomorrow evening, but he won't be on the bench tomorrow night."
With Wayne Rooney also absent due to a head injury, England manager Hodgson is expected to turn to United striker Danny Welbeck to lead the line against the Moldovans.