After four matches on the trot without a goal, coach Didier Deschamps elected to plump for the 27-year-old Gignac, who has scored three goals in three outings for Marseille in Ligue 1 this season.
Gignac won the last of his 16 caps at the 2010 FIFA World Cup™, but Cabaye will not add to his solitary cap, paying for his lack of game time at English Premier League club Newcastle.
"We have to win (against Georgia)," the 1998 FIFA World Cup-winning captain told AFP. "We'll have in front of us a Georgia team that has nothing to lose and will fight like the away match (which the French won 3-1). We have to get ourselves in tournament mode and not that that we're superior and that we'll win."
Deschamps added: "There's no such thing as an easy international these days. There are three points to play for and they won't gift them to us. Georgia didn't give up until the end against Spain (losing 1-0) and almost equalised in the final minute.
France are second in Group I, one off leaders Spain.