"We are not afraid of the big names, specifically Ghana. We know that we are capable of qualifying," Mohamed 'Mazda' Abdallah, Sudan coach.
Quarter-finalists at South Africa 2010, Ghana are aiming to reach a third consecutive FIFA World Cup, but standing in their way will be a pair of dark horses in Sudan and Zambia.
Six-time champions, Egyptian giants Al Ahly, must overcome a two-goal deficit this weekend or face missing the final stage of the Champions League.
Former champions Ismaili claimed a 1-0 win away to Sudan's Al Hilal, but fellow Egyptian side Al Ahly fell 2-0 to Ittihad in the first leg of the third round.
The Indomitable Lions and the Super Eagles booked their places at South Africa 2010, while Egypt and Algeria face play-off on Wednesday.
Algeria or Egypt? Cameroon or Gabon? Tunisia or Nigeria? A dramatic conclusion ensues as Africa's last three places at the FIFA World Cup are seized.