Paraguay continue to set the standard in South America, where their 1-0 victory in Colombia was the headline result on a day that also witnessed home wins for Bolivia and Argentina.
Bolivia kicked off Satuday's action with a convincing win against Peru at home in La Paz. Joaquin Botero was the hero of the day for the Bolivians, scoring a pair of goals in the 3-0 win at the Hernando Silas stadium.
The Bolivar hit-man struck first after only four minutes, getting on the end of a fine cross. He then flicked home a header from Joselito Vaca's free-kick in the 16th minute, his two-goal performance more than making up for a missed penalty. Ronald Garcia added a third late in the game as the result sees Bolivia step off the foot of the South American qualifying table, now one point ahead of the struggling Peruvians.
Saturday's second game saw Argentina eke out a result against ancient rivals Uruguay in Buenos Aires. Lionel Messi opened the scoring for the Albiceleste after only six minutes before Sergio Aguero smashed home a second seven minutes later to make it 2-0.
Diego Lugano pulled one back one back for the visitors five minutes from the break, but their hosts managed to hang on to the lead. The 2-1 win now sees Argentina move into second place in the continental standing, one point behind surprise leaders Paraguay - for a while at least.
Paraguay, after all, wasted no time in re-establishing their four-point lead at the top of the South American standings by beating Colombia 1-0 in Bogota. Salvador Cabanas scored the only goal of the game for the away side on nine minutes.
Colombia remain in sixth place on ten points, having now suffered three losses in succession.
South American Zone results
Saturday 11 October
Bolivia 3-0 Peru
Argentina 2-1 Uruguay
Colombia 0-1 Paraguay
Sunday 12 October