Switzerland and Slovakia seized Europe's last two automatic berths in South Africa, while Portugal, Greece, Slovenia and Ukraine made the play-offs.
Andrei Arshavin was on target as Guus Hiddink's Russia concluded their Group 4 qualifying campaign with a 1-1 draw against Azerbaijan.
Russia coach Guus Hiddink says that playing for pride should be motivation enough when his side negotiate their final qualifier in Azerbaijan.
Switzerland, Greece, Slovakia and Slovenia head into Wednesday's final qualifiers hoping to claim the two remaining direct tickets to South Africa.
Italy, Germany, Denmark and Serbia all sealed their places at South Africa 2010 with positive results during Saturday's nervy round of qualifiers.
Azerbaijan moved off the bottom of South Africa 2010 qualifying Group 4 courtesy of their first ever away win at the expense of Liechtenstein in Vaduz.