Nine teams from CONCACAF will move on to the group stages at the weekend, while nine more will have to contemplate where it all went wrong.
Bermuda beat Caribbean giants Trinidad and Tobago on a weekend which saw the US stroll and Mexico edge Belize in nervy fashion.
Brian Ching scored three goals to help the USA to an 8-0 win over Barbados in the opening match of a two-leg FIFA World Cup qualifying tie.
Landon Donovan is feeling the heat ahead of USA's opening qualifier against Barbados, as FIFA.com found out in an exclusive interview.
Wednesday was a fateful day in CONCACAF as Grenada hammered USVI, Belize made a date with Mexico and Barbados squeaked through.
Wednesday's slate of CONCACAF qualifiers had a little bit of everything - a 12-0 drubbing, a few upsets and a first-ever win on home soil.