Malawi, Mozambique, Rwanda and Sudan are among the teams through to the final round of CAF qualifying, but Senegal and Congo DR are out.
Senegal were the only major side to fall as Round Three of the African qualifiers for the 2010 FIFA World Cup South Africa entered the final straight.
With so many places still up for grabs and a plethora of potential outcomes, FIFA.com takes you through the possible scenarios group-by-group.
FIFA has decided against all games on the final matchday of the African Zone qualifying for South Africa 2010 kicking off simultaneously.
Benin won to join Nigeria and Cameroon in the third phase of African Zone qualifying, while Côte d'Ivoire and Egypt are on the brink of progression.
Mohamed Aboutrika's 30th-minute strike gave Egypt a 1-0 win over Congo DR, opening up a three-point gap at the top of Group 12.