The Munich Air Disaster decimated Manchester United. Just ten years later, however, a man who had barely survived the tragedy guided a new team to European Cup glory.
Manchester United have lifted the English top-flight title for the 20th time, and FIFA.com looks back on the club's journey from first championship to last.
David Beckham has hailed Sir Alex Ferguson as the greatest manager in football after the Manchester United boss announced his retirement, with Sir Bobby Charlton and Bryan Robson also offering their admiration.
Sir Bobby Charlton believes Bayern Munich are the team to beat in this season's UEFA Champions League, and has labelled Borussia Dortmund as contenders and hailed the passion of their fans.
Ahead of the eagerly awaited last 16 clash between Real Madrid and Manchester United, we look back on four of these European giants' most memorable meetings.
Exactly fifty-five years ago, the world was rocked by the news that Manchester United's young team had been involved in a plane crash.