Alberto Acosta bagged a hat-trick as Tigres Monterrey hammered Pumas UNAM 5-0, Queretaro remain without a win this season, while Club America came from behind to beat Leon 2-1.
Ten-man Morelia extended their unbeaten start to the Mexican Apertura by winning 3-1 at Leon, while Jaguares beat Queretaro to claim their first victory of the campaign.
Morelia roared back to secure a 3-2 win over San Luis in the Mexican Apertura, moving the club away from the bottom of the standings into 15th place.
Ten-man Emelec grabbed a last-gasp goal to beat Avai 2-1, while Goias defeated Penarol and Atletico Mineiro triumphed over Santa Fe in other Copa Sudamericana last-16 first-leg action.
