Cristiano Ronaldo hit a second half hat-trick to see off Northern Ireland in Belfast, after the hosts had led at the break. There were three red cards in an ill-tempered game as Helder Postiga, Chris Brunt and Kyle Lafferty were all dismissed.
Ahead of Monday's FA Cup match-up with Reading, Manchester United manager Sir Alex Ferguson discussed Nemanja Vidic's introduction back into the first team as the Serbian centre-back recovers from his second major knee injury in less than two years.
Manchester United defender Jonny Evans has signed a new three-and-a-half-year contract which will keep him at Old Trafford until 2016.
Manchester United had to come from behind to secure three points against Queens Park Rangers, Everton were denied victory by a late equaliser, while Jordi Gomez bagged a hat-trick for Wigan Athletic.
It proved a tough evening for some of Europe's biggest clubs as Barcelona and Manchester United edged narrow wins, while champions Chelsea were beaten at Shakhtar Donetsk. FIFA.com reviews the UEFA Champions League action.
With the help of two early corner kick goals, Manchester United cruised to a 3-0 victory over Newcastle United.