PSV Eindhoven knocked FC Twente off top spot in the Eredivisie with a 3-0 win over their title rivals, while Vitesse Arnhem missed an opportunity to go top by losing 3-1 at VVV Venlo.
Viktoria Plzen stunned UEFA Europa League holders Atletico Madrid with a 1-0 win to top Group B, while Lazio cruised to victory at Maribor to finish top of Group J ahead of Tottenham Hotspur.
Tim Matavz scored twice as Slovenia picked up their first points of the FIFA World Cup qualifying campaign at the expense of Cyprus in Maribor.
PSV Eindhoven began their Eredivisie campaign with a surprise 3-2 defeat against RKC Waalwijk, while the day's other two games both finished in a 1-1 stalemate.
Tim Matavz scored in injury time to seal PSV Eindhoven a thrilling 3-2 win over AZ Alkmaar, while FC Twente slipped down to fourth after a 2-2 draw at NAC Breda.
AZ Alkmaar's lead atop the Eredivisie standings has been reduced to just one point, with chasers PSV Eindhoven claiming a 2-0 win over VVV-Venlo and FC Twente beating Roda JC.