Being born in France, Khaled Lemmouchia began his club career at the age of 16 in 1997 at the Olympique Lyonnais academy, but his first professional contract came from back home, specifically with Algerian giants ES Setif in 2006, where he still plays until the present. He has excelled with the club, winning the Algerian League title twice (2007 and 2009) and the Arab Champions League also twice (2007 and 2008).

His debut with the Algerian national team came in 2008 against Senegal which Algeria lost 1-0. Since then he has made over a dozen appearances with the Desert Foxes including most of the qualifiers for the 2010 FIFA World Cup, his last being the intense encounter against Egypt in Cairo which the Algerians lost 2-0. In January of this year, he flew with the squad to Angola to participate in the CAF Africa Cup of Nations, however, he left before playing a single game due to an altercation with the Algerian coach Rabeh Saadane.