Marseille winger and France international Mathieu Valbuena faces up to a month out of action after suffering a collarbone injury during his side's 1-0 Ligue 1 defeat at Lille.
Ghana winger Andrew Ayew suffered a torn meniscus during the Black Stars' second leg play-off against Egypt in Cairo on Tuesday, leaving the Marseille man out of action for around eight weeks.
Paris Saint-Germain remained unbeaten in their Ligue 1 campaign after a 2-0 win over Toulouse, while Marseille also logged a 2-0 win against Lorient and Nice edged Guingamp 1-0.
Goals from Theo Walcott and Aaron Ramsey allowed Arsenal to escape the Stade Velodrome with three points after beating Marseille 2-1 in their first game of the UEFA Champions League group stage.
Kevin-Prince Boateng and Michael Essien are just some of the big-names returning to action as 40 African nations vying for a spot in Brazil is reduced to ten for the final round of 2014 FIFA World Cup Brazil™ qualifying.
Ghana and Marseille star Andre Ayew speaks to FIFA.com about his memories of South Africa 2010 and his belief that the Black Stars should be aiming to establish themselves among the contenders for major trophies.