Sevilla comfortably beat derby rivals Real Betis 4-0, keeping Betis at the bottom of the La Liga table, while Villareal and Espanyol both marched to straightforward victories.
David Villa ended his seven-game scoring drought with a double against Real Betis as Atletico Madrid closed to within a point of Barcelona, while Villarreal thrashed Valencia 4-1 at the Madrigal.
A 3-0 victory for Villarreal has kept their 100 per cent record in the Spanish La Liga going this season, while Real Valladolid got themselves their first win on the board, seeing off Getafe 1-0.
Nigeria coach Stephen Keshi and new Super Eagles forward Victor Moses both say their best is yet to come after a mixed start to Brazil 2014 qualifying.
Derek Asamoah made his recall to the Ghana squad count, scoring the winner in a 2-1 friendly win over Gabon, while Kalu Uche and brother Ikechukwu secured a 2-0 win for Nigeria over Zambia.
Former Nigeria captain Stephen Keshi was denied victory in his first game as coach of the national team as Botswana held firm to earn a 0-0 draw in their friendly in Benin City.