A superb four-goal show from Robert Lewandowski earned Borussia Dortmund a 4-1 win at home to Real Madrid in the first leg of their UEFA Champions League semi-final.
Atletico Madrid are still in the race for a top-two finish in La Liga after a convincing 5-0 win over Grenada, while Barcelona topped hosts Real Zaragoza 3-0.
Initially going a goal down to visiting Levante, Real Madrid stormed back for five goals to go 12 games unbeaten in La Liga as Barcelona also notched five goals against Real Mallorca and Real Sociedad beat Malaga 4-2.
Real Madrid put one foot in the semi-finals after goals from Cristiano Ronaldo, Karim Benzema and Gonzalo Higuain gave them a 3-0 win at home to Galatasaray.
Chile host Uruguay in what looks set to be a crucial game in the hunt for an automatic South American FIFA World Cup™ qualification place, while leaders Argentina visit Bolivia and Colombia travel to Venezuela.
Lionel Messi once again led the way as Argentina cruised to a 3-0 victory over Venezuela to reinforce their grip on top spot in CONMEBOL qualifying for Brazil 2014, while Colombia and Peru also both scored important wins.