Roy Hodgson said he will not be able to take a full-strength squad to England's pre-FIFA World Cup training camp in Portugal if a Premier League team makes it to the UEFA Champions League final.
Tottenham Hotspur began their 2013/14 English Premier League campaign with a 1-0 win over Crystal Palace, while Jose Mourinho marked his return to Stamford Bridge as Chelsea manager by beating Hull City 2-0.
Manchester City defender Joleon Lescott has been called up to the England squad for the FIFA World Cup qualifying games against San Marino and Montenegro, with Aaron Lennon and Michael Dawson out with injuries.
Arsenal couldn't recover from two first half goals from Gareth Bale and Aaron Lennon, giving Tottenham Hotspur the three points from Sunday's north London derby.
Clint Dempsey saw some late sustained pressure from Tottenham Hotspur finally pay-off in the dying seconds of their game with Manchester United, cancelling out Robin Van Persie's opener to grab a point.
Manchester United beat West Bromwich Albion as Manchester City kept pace with the leaders thanks to a thrilling 4-3 win at Norwich City. Elsewhere, Stoke City and Southampton drew 3-3 and Aston Villa again lost heavily.