Atletico Madrid claimed top spot in the La Liga table with a 2-0 win at Celta Vigo, while Barcelona and Villarreal lost to Real Valladolid and Granada respectively.
As kick-off in Brazil looms over the horizon, we preview the week's friendly action as a number of FIFA World Cup hopefuls lock horns, with Spain-Italy and France-Netherlands the standout games.
Atletico Madrid have confirmed that David Villa has suffered a hamstring strain, putting in doubt his participation in the Copa del Rey final against Real Madrid.
Real Madrid were held to a 1-1 draw against Athletic Bilbao with Cristiano Ronaldo sent off in the second half, while Atletico Madrid became outright leaders for the first time in 18 years with a 4-0 win over Real Sociedad.
Barcelona and Atletico Madrid remain atop the Spanish La Liga table on 54 points after Barça beat Malaga 3-0 and Atleti took down Rayo Vallecano 4-2, while Athletic Bilbao saw off Osasuna, comfortably winning 5-1.
Atletico Madrid and Barcelona were held to 1-1 draws with Sevilla and Levante respectively, missing out on an opportunity to create some distance at the top of the Spanish La Liga table as Villareal earned a 2-0 win over Almeria.