Goals from captain Xavi and Alvaro Negredo put Spain to within a point of a guaranteed spot at next summer's FIFA World Cup, as Vicente Del Bosque's side overcame a stubborn Belarus team 2-1.
CSKA Moscow stretched their lead at the head of the Russian Premier League to seven points after a 1-0 home win over Krasnodar, while closest rivals Anzhi Makhachkala stumbled to a 1-1 draw against Krylya Sovetov.
CSKA Moscow climbed to top of the table in a come-from-behind 3-2 win over Volga Nizhny Novgorod while Brazilian star Hulk opened his Russian Premier League goalscoring account.
On a day which saw 720 minutes of footballing action at the 2012 Olympics, the quarter-final line-up was decided with some unfancied names still in contention and favourites leaving London.
Samuel Eto'o was on target as Anzhi Makhachkala won 3-0 at Spartak Moscow, Krylya Sovetov beat ten-man Rostov 2-1, while Lokomotiv Moscow and Rubin Kazan drew 0-0.
Romania's slim hopes of qualifying for UEFA EURO 2012 were ended tonight as they were held to a draw at home to Belarus.