Sevilla midfielder Piotr Trochowski will be out for around eight months after a knee operation in the USA.
Barcelona came from two goals behind to beat Sevilla 3-2 and maintain their perfect La Liga record, Malaga thrashed Real Betis to move into second, and Valencia claimed their second victory of the season.
Real Madrid fall to eight points behind La Liga leaders Barcelona after Piotr Trochowski's volley with just over a minute on the clock was the difference as Sevilla won 1-0.
Sevilla's German midfielder Piotr Trochowski speaks to FIFA.com about adapting to life in La Liga and his hopes of earning a late recall to Joachim Low's national squad for UEFA EURO 2012.
Sevilla picked up their first win since early December under new head coach Michel, defeating Osasuna 2-0 through Gary Medel and Piotr Trochowski goals.
FIFA.com rounds up the eye-catching early deals that have provided the opening action in the current transfer window, with the likes of Nuri Sahin, Ruud van Nistelrooy and Manuel Neuer among those on the move.