Italy and the Netherlands stole the headlines by becoming the first European nations to qualify for Brazil 2014, while Germany, Switzerland and Russia each took a giant stride towards booking their passage.
Second-half goals from Vasili Berezutskiy, Alexander Kokorin and Denis Glushakov earned Russia a 3-1 win at home to Israel that sent above Portugal and to the Group F summit.
Lille secured their first win in Group B of the UEFA Champions League with a 2-0 defeat of CSKA Moscow as Vasili Berezutsky put into his own net before Moussa Sow put the result beyond doubt.
Jose Mourinho came out on top against former club Chelsea in the Champions League as Inter won 2-1 while Sevilla claimed a 1-1 draw at CSKA.
FIFA.com tells the story of football's twins, the siblings who invariably spell double trouble whether lining up together or crossing swords.