Alianza and Motagua are riding high once more after ending their respective title droughts in El Salvador and Honduras. FIFA.com tells the story of their renaissances.
Honduras captain Amado Guevara has urged his team-mates to play for a famous victory against a Spain side who are "not invincible."
Honduras have been making their way up the global standings as they prepare to make their long-awaited return to the game's biggest stage.
Celebrations have overtaken the whole of Honduras since dramatic events saw the Catrachos clinch a berth at South Africa 2010.
With just one direct qualifying ticket remaining in the CONCACAF zone, Central Americans Costa Rica and Honduras face a nervy final matchday.
Honduras defeated Trinidad and Tobago 4-1 in their South Africa 2010 qualifier to dampen the Soca Warriors slim hopes of reaching next year's finals.