The Albiceleste edged Nigeria 1-0 in their Group B opener before crushing Korea Republic 4-1 and while the Barcelona star had plenty of chances to score in both encounters he was denied by great goalkeeping.
"It's not a problem," said Messi. "The important thing is that I had opportunities and although the ball didn't go in, eventually it will."
Heading into the FIFA World Cup, the 22-year-old had endured difficult times in the Argentina shirt under coach Diego Maradona.
He still averages less than a goal every three games at international level, a disappointing tally for the FIFA World Player of the Year but said: "The goal will come.
"I am happy that Gonzalo Higuain scored a hat-trick against South Korea and I am delighted for the team. We took a step forward with respect to our opening game and hopefully we will take another one in our next game."
Maradona's side top Group B heading into Tuesday's match against Greece in Polokwane. Argentina need a point to be sure of a place in the last 16 although they can afford to lose if Korea Republic fail to beat Nigeria.
"We are in a good position," said Messi. "We have almost assured ourselves a place in the next round so everyone is calm and looking forward to our next game."