Oscar Tabarez's side are training in Kimberley ahead of their showdown against Les Bleus and Lugano said: "We will arrive at the game with France in our best form.
"We will see how far we can go in the competition but we are calm because we have worked well in training and we are ready."
Uruguay also take on tournament hosts South Africa and Mexico in Group A.
"Our conscience is clear," Lugano added. "We have done everything possible to arrive at this game in the best possible condition."