Ferdinand's error four days ago in Dnipropetrovsk meant one enforced change, with Robert Green suspended after being sent off trying to mop up the problem, while Wayne Rooney picking up a calf injury and Steven Gerrard's groin complaint accounts for two others. Capello has stressed the need for "plan A, B and C" with or without talisman Rooney, but Ferdinand is a certain starter at Wembley when England wrap up their Group 6 campaign.
"Rio will play against Belarus," Capello said. "I have big confidence in Rio. He will play and I'm sure he will get better with every game. I spoke with Rio, on Monday and this morning, and I will speak also with some other players. We will see the DVD of the game to understand what happened and I will see the mistakes."
Capello's message is that England's work is not done, despite eight wins from nine qualifiers. Gareth Barry was left out against Ukraine, illustrating how no place can be taken for granted.
"There's no guarantee of the place and we won't always play the same style," Capello said. "We need to play other styles - style A, B, C. It depends on the opposition and the style of the game we need to play. I will do some experiments against Belarus. It's possible to see a different style on the pitch and that will be very interesting for me. For me, it is a lot of experiments."
Rooney has been England's top goalscorer on the path to South Africa but Capello is keen to see how his team play without the Manchester United forward. "Rooney is a very important player for us and Manchester United," he said. "For this reason we will play a different style against Belarus, with some different players.
"It will be a very interesting game for me. From this experience I will know some players better. I have big confidence in all the players. Rooney is important because the style of Rooney is the style I like in my team. He is an important player but we have others. We can win with Rooney and without Rooney."
The onus on Rooney has increased partly due to Emile Heskey providing bulk rather than goals, with the Aston Villa striker in the headlines recently as he is not playing regularly for his club and may need to move to stay first-choice for his country. Capello, outlining his criteria for FIFA World Cup players, said: "First they have to be fit. We will have all the players without problems. They have to play a part in the final part of the league."
Heskey's chances at Villa Park have been limited due to the form of Gabriel Agbonlahor, who could feature against Belarus. "If he is fit," Capello said. "He had a little problem with his back but he will be okay and it is possible that he will be in the starting XI."
Capello will also make a late check on goalkeeper David James, who missed training with a knee problem. "He is getting better and stayed with us," Capello added. "I will decide on the day of the game. I have to speak with him."
Carlton Cole may not have improved his chances by being last out of the changing rooms and joining up with the squad slightly late. He was part of a 22-man party who trained at Arsenal's London Colney complex, with Gerrard departing from the session with physio Gary Lewin after starting a 10-v-10 practice match.
"He tried to practice in training but after 10 minutes had to stop," Capello said. All the players who have been involved in the qualifying campaign have been invited to Wembley as guests, but Capello is not sure that everyone will be available.
"This is the family of the England team," Capello said. "We invited all the players but I'm sure not all of them will be here because there will be training the following day and it is a long trip for some players in the north. For this reason we will happy for those here and happy for those who are not here."