Premier League leaders Liverpool are set to be without star striker Fernando Torres for the fourth successive match when Portsmouth arrive at Anfield on Wednesday.
The Spanish international is still recovering from a hamstring injury and, although he trained today, this weekend's match against Tottenham Hotspur is seen as a more realistic target for a comeback appearance.
Torres's fellow forward Robbie Keane is still troubled by a groin problem. Portsmouth are set to again be without injured defenders Sol Campbell and Glen Johnson for what will be Tony Adams's first match as Pompey manager, following his appointment as successor to Harry Redknapp.
Younes Kaboul and Noe Pamarot are set to deputise again, while Lassana Diarra is also in line to play at Anfield despite limping off near the end of last weekend's 1-1 draw at home to Fulham.
Adams does have options in midfield with Sean Davis, back from a one-game suspension, and the fit-again Niko Kranjcar, who played six minutes as a substitute against Fulham, both in contention for starting spots.
Cole and Cahill boost employers
Chelsea, looking to bounce back from the disappointment of having their 86-game unbeaten home run in the Premier League ended by Liverpool last weekend, will have Joe Cole available for Wednesday's match away to Hull City. The England attacking midfielder has been sidelined for the past three weeks by a foot injury.
However, Didier Drogba, Michael Ballack and Michael Essien are all set to miss the journey to the KC Stadium.
Australian Tim Cahill will return to the Everton midfield for their match away to fellow strugglers Bolton Wanderers, after serving a three-game ban for being sent-off in last month's Merseyside derby, while his team-mates Yakubu and Nuno Valente will both have their fitness assessed on the morning of the match.