Champions could be crowned in Morocco and Uruguay this weekend, while places in the final of the Chliean Apertura and Mexican Clausura are up for grabs. With four of the leading contenders squaring off in Argentina and Korea Republic, and Round 3 unfolding in Brazil, FIFA.com anticipates the forthcoming action.
Argentinian Clausura: Red hurdle for leaders
Six teams will take realistic title aspirations into the fourth-last round, although much could change as four of them collide. Estudiantes sit two points clear of River Plate at the top, but they face a tall hurdle in the shape of Independiente, whose current run of 16 points from possible 18 has taken them to within six points of their forthcoming opponents.
Level on points with El Rojo, Velez Sarsfield must beat third-placed Boca Juniors, who will have one eye on their upcoming Copa Libertadores semi-final against Fluminense, to maintain their glory charge.
Big games: River Plate and fourth-placed San
Lorenzo will expect three points from the visits of Huracan and
Players to watch: Ezequiel Maggiolo has struck thrice in his last two matches to earn Estudiantes slender victories, but in Independiente's Walter Fabian Assmann he will be trying to score past a goalkeeper who has leaked just one goal in his past five games.
Brasileiro: Holders seek kick-start
Sao Paulo's attempt to win the Copa Libertadores and line up alongside Manchester United, Pachuca and Waitakere United at this year's FIFA Club World Cup evaporated midweek, and they will now strive to kick-start their bid for a record third straight Brasileiro gold at home to Coritiba.
With one point on the board, O Tricolor Paulista sit five adrift of the co-leaders, both of whom face stern tests in Round 3; Nautico at Gremio and Cruzeiro at home to Santos.
Big game: Vasco and Botafogo, both on three
points, will meet in a Carioca derby at the
Players to watch: With key players sidelined, Flamengo will need wingback Leonardo Moura to be at his creative best against Internacional, whose attack will comprise Fernandao and Nilmar.
Uruguayan Clausura: Penarol, River Plate or
The concluding round of the Clausura will culminate with either Penarol or River on top of the podium - or an ensuing play-off to determine which of the Montevideo sides will seize the prize. Neck and neck going into battle, the pair will, ironically, host two teams who are also level on points.
Penarol appear to have the tougher task given that Rampla Juniors have won their last three matches, but they will nonetheless expect their sixth successive win. River, meantime, will be confident of seeing off Juventud.
Big games: Three teams, all level on points, could
finish third. Defensor and Liverpool face trips to Bella Vista and
Tacuarembo, while Nacional entertain Cerro.
Players to watch: Penarol's chances of success rest heavily on the shoulders of forwards Fabian Estoyanoff and Carlos Bueno, while 18-year-old sensation Jonathan Urretavizcaya will be charged with inspiring River to victory.
Moroccan GNF 1: Big test for frontrunners
Two points clear and having played a game less than the three teams directly beneath them, FAR Rabat have their destiny firmly within their own hands and could even be crowned this weekend. In fourth-placed Hassania Agadir, however, they will entertain a team that has conceded just one goal in eight matches and is unbeaten in over three months.
An away victory in the capital would be welcomed by Khemisset, who would then go top if they beat fifth-placed Difaa El Jadida in their penultimate match.
Big game: Five points off the pace in third, Raja
Casablanca must overcome struggling Oujda at home and hope the
leaders drop points to stay alive in the title race.
Players to watch: The influence of FAR Rabat's Abderrahman Lemsasi and Omar Najdi of Agadir has become evermore apparent as the season has progressed.
Korean K-League: Top four lock horns
Most players would be content with four goals in two games. Not Pohang Steelers forward Denilson, who claims he would have doubled his brace in a win over Gyeongnam last time out had it not been for eating too much lasagne at coach Sergio Farias' home. The defending champions, eight points off the pace in third, will be hoping goals are on the Brazilian's menu when they take on leaders Suwon Samsung Bluewings.
Thereafter, runners-up Seongnam Ilhwa Chunma, who sit one point above Pohang, will take on fourth-placed FC Seoul.
Big game: Jeju United staged a late fightback to
win 4-2 at Daegu and escape the foot last weekend, and they will
look to carry that momentum into their meeting with Gwangju Sangmu
Players to watch: Shuba has found the target in each of his past four appearances for struggling Chunnam Dragons, while Enio has scored in his past three outings for mid-table Daegu. Who will win their shootout on Sunday?
Everton will protect a 3-1 first-leg lead when they host Universidad de Chile in their Chilean Apertura semi-final. With a final against their arch-rivals Colo Colo at stake, however, the Santiago giants can not be counted out.
Cruz Azul, 1-0 winners away, will welcome San Luis to Mexico City on Sunday looking to complete the job and reach the Mexican Clausura play-off final. Santos Laguna will host Monterrey in the other semi-final, second leg with the tie evenly poised at 1-1.