Second half goals from Luca Toni and Hamit Altintop lifted UEFA Cup favourites Bayern Munich through to the group stages with a 2-0 win over Portuguese side Belenenses on Thursday.
On a charged programme across the continent other clubs celebrating their pass to the group stages where English Premiership outfits Tottenham, Everton and Bolton, and Scottish top-flight side Aberdeen.
But two clubs that didn't make it past Thursday's first round second leg ties were the fourth Premiership side Blackburn and Ajax, the former European Champions who were knocked out by Dinamo Zagreb.
The Croatian outfit came good on the away goals rule after a 3-2 extra time win in a heated encounter over the Dutch masters which featured eight yellow cards.
Bayern Munich are appearing in Europe's second club competition after missing out on the coveted Champions League by only finishing fourth in the Bundesliga last season.
And Ottmar Hitzfeld's Bavarian giants avoided the ignominy of slipping up at the first hurdle when building on their first leg lead to go through 3-0 on aggregate - watched by a sparse crowd of around 4,000 fans - in Portugal.
"We did our job here, but it was an unusual task in front of so few spectators," said Hitzfeld after the game at the Estadio do Restelo.
He added: "The tension was missing a little. I was pleased when we went 1-0 up, more because our game improved and we really took control."
Toni, who scored Bayern's first goal after 59 minutes, said: "Belenenses played very well and were well organised. The team did well to come here and get a result."
Aberdeen completed a week to remember for Scottish football when following up Rangers and Celtic's heroics in the Champions League by booking their place in the group stages with a 1-1 draw away to Dnipro for a 2-1 aggregate win.
Darren Mackie could not have come up with a better time to produce his first header of the season when grabbing Aberdeen's all important goal in the 27th minute.
The win came after Rangers had stunned French champions Lyon and city rivals Celtic meted out the same treatment to European champions AC Milan.
Aberdeen manager Jimmy Calderwood told BBC Scotland: "It's great for Scottish football. Gordon (Strachan) and Walter (Smith) have done great and now we have too. Maybe we're not as bad as people think!"
Tottenham were held to a 1-1 draw by Anorthosis in Larnaca but that was sufficient after their 6-1 thrashing of the Cypriots in London in the first leg to see them through 7-2 on aggregate.
Robbie Keane saved under-fire coach Martin Jol from an embarrassing defeat when the Irish international came off the bench to cancel out Fabio De Matos Pereira's 54th minute goal.
Jol said: "It would have been better if we could have kept a clean sheet because it was one of our targets - the only thing we could gain at 6-1 up.
"I have to think positively and for me it's great that Tottenham are in Europe again. We had a couple of thousand supporters here and it is always good to see them happy."
Everton produced a battling second-half display to beat Metalist Kharkiv 3-2 on the night and 4-3 on aggregate.
David Moyes's men looked to be struggling at the interval at 1-0 down but goals from Joleon Lescott, James McFadden and substitute Victor Anichebe sealed the win.
In form Nicolas Anelka came off the bench to produce the 68th minute winner to send Bolton through 2-1 on aggregate against Macedonian leaders Rabotnicki Kometal.
Blackburn were up against it trailing Greek side Larissa 2-0 after the first leg, and Silva Cleyton's 17 minute strike left Mark Hughes's team needing four goals at Ewood Park.
Matt Derbyshire scored a retaken penalty in first-half injury-time after David Dunn was felled and Stephen Warnock fired a fine second on the volley from David Bentley's cross six minutes after the break - but it proved insufficient.