A total of 52 clubs have entered for next year's competition.
The draw for the club competition staged on Monday in Marrekech, Morocco, sees several past winners of Africa's foremost clubs competition including Zamalek, Enyimba and Raja Casablanca will be involved in the preliminary rounds.
Two-time winners Enyimba will first host Ange de Notse of Togo, while Zamalek face AS Douanes of Niger and Raja are up against Diamond Stars of Sierra Leone.
Atlabar will become the first club from South Sudan to feature in this competition and they are drawn against Ghana's Berekum Chelsea.
The preliminary rounds will kick off on the weekend of 7-9 February, while the return leg matches will be played a week later.
The Round of 16 matches will be played between 28 February to 9 March, while the final qualifying round are slated for between 21 and 30 March.
In the CAF Confederation Cup, 42 clubs will compete for the top prize.
This year's winners CS Sfaxien as well as runners-up TP Mazembe have opted for the more prestigious Champions League.
Nigerian pair Bayelsa United and Warri Wolves have been given byes as well as Asec Mimosas (Côte d'Ivoire), MAS (Morocco), Djoliba (Mali), Ismaily, Wadi Degla (Egypt), Zesco United (Zambia), Al-Ahly Shandy (Sudan) and Etoile du Sahel, CA Bizerte (Tunisia).
The first leg preliminary round matches will begin on 7 February.