English Premier League leaders Arsenal were handed a mouthwatering tie against north London rivals Tottenham Hotspur in the third round of the FA Cup.
Arsenal's most recent piece of silverware came in the 2005 FA Cup but if they are to repeat that success this season they will have to overcome Spurs at the first hurdle after the two sides were paired together in the pick of Sunday's draw.
The pair are among the most successful clubs in the competition's history, with Arsenal having lifted the trophy on ten occasions while Spurs have won it eight times.
The only side to have won the FA Cup more times are Manchester United, who will also be involved in an all-Premier League tie in the third round after being paired at home to Swansea City.
United might have been hoping for a more favourable cup draw following a disappointing start to the defence of their league title which has seen them lose five times in 15 matches under new boss David Moyes, with their latest setback Saturday's 1-0 loss to Newcastle United at Old Trafford.
United have won the FA Cup 11 times, but the last time was back in 2004. FA Cup holders Wigan Athletic start off against MK Dons while the side they beat in May's final, Manchester City, face a short trip to Blackburn.
Liverpool, who moved up to second in the Premier League standings with their 4-1 win over West Ham United on Saturday, could face Oldham in their third-round tie - the team that knocked them out last season.
Oldham beat the Reds 3-2 in the fourth round and they will get another crack at Brendan Rodgers' men if they can overcome Mansfield in their second-round replay.
There are a number of other all-Premier League ties, with in-form Newcastle hosting Cardiff City, Norwich City taking on Fulham and Crystal Palace going to West Bromwich Albion.
The top three sides in the Championship, meanwhile, are all away to top-flight opposition with leaders Burnley at Southampton, second-placed Queens Park Rangers going to Everton and Leicester City in third taking on Stoke City.
Steve McClaren's Derby County, who are up to fourth in the second tier after winning their last five matches, were handed a home time against a Chelsea side looking to win the cup for a fifth time in eight seasons
Nottingham Forest, fifth in the Championship, will also need to claim a Premier League scalp if they are to reach the fourth round after being drawn at home to West Ham.
In ties involving the other top-flight teams, Aston Villa take on Sheffield United, Middlesbrough meet Hull City while rock-bottom Sunderland host Carlisle.
Of the non-league clubs still involved in the competition, Kidderminster were drawn against Peterborough, Grimsby face Huddersfield while Macclesfield are up against Sheffield Wednesday.
Another conference side, Wrexham, will go to Charlton if they can overcome League Two pacesetters Oxford in their second-round replay.
In other games, last season's semi-finalists Millwall are at Southend, Brighton welcome Reading, Bolton take on Blackpool, League One leaders Leyton Orient go to Yeovil, Rochdale face Leeds, Ipswich clash with Preston, Bristol City take on Watford, Doncaster face Stevenage and Plymouth go to Port Vale.
Also, Barnsley host Hartlepool or Coventry, Birmingham meet Bristol Rovers or Crawley while Bournemouth take on Fleetwood or Burton.