Olympiacos clinched their 40th
A brace from Avraam Papadopoulos either side of the break was enough to get Michel's men in the party mood, with the centre-back following up his 14th-minute strike with a decisive header in the 56th minute.
The Karaiskakis Stadium was already rocking when Djamel Abdoun put the Reds out of sight by rifling home a firm effort in the 62nd minute. But amid the celebrations, 11-time champions AEK dropped to within a single point of Aris Salonika and the relegation zone.
Aris had earlier extended their unbeaten home run to a seventh game with a comfortable 4-0 win over Levadiakos in Thessaloniki. Nuno Coelho needed just two minutes to open the scoring with Giannis Gianniotas completing a brace before Andreas Tatos added gloss to the win ten minutes from time.
Elsewhere, Giannina consolidated their outside chance of qualifying for Europe as Fotis Georgiou's 69th-minute goal settled a 1-0 win at FC Xanthi, while Veria played out a goalless draw with OFI Crete.