Bert van Marwijk has stepped down as Netherlands coach, the Dutch FA (KNVB) has announced.
The 60-year-old's resignation follows a disappointing showing at UEFA EURO 2012, in which Oranje were knocked out at the group stage without taking a point.
A statement on the KNVB's website said: "On the initiative of Bert van Marwijk, the KNVB and Bert van Marwijk decided on Wednesday to end the coach's contract with immediate effect.
"The agreement between the FA and coach officially ran until the 2016 European Championship."
The Netherlands arrived in Poland and Ukraine as one of the favourites for the title after finishing runners-up to Spain at the 2010 FIFA World Cup™ in South Africa.
However, they failed to get out of a Group B containing Germany, Denmark and Portugal, losing all three of their matches to finish at the bottom of the table.
The failure prompted the KNVB to hold a number of meetings with Van Marwijk about what went wrong. And the coach opted to leave his post, albeit reluctantly, a decision which was accepted by the governing body.
"I have severe doubts, but have decided to take this step anyway," Van Marwijk said in a short statement.
The head of the KNVB, Bert van Oostveen, added: "The KNVB are grateful to Van Marwijk. He has performed exceptionally well in the World Cup finals and took them to first place in the FIFA rankings.
"I personally had a very good feeling about our co-operation. Of course it is sad to part early, but we must be realistic."
Van Marwijk, who has previously held the reins at Feyenoord and Borussia Dortmund, took charge of the national team in 2008.
The KNVB will now begin the search for his successor, with the Netherlands aiming to have a new coach in place before their friendly against Belgium on 15 August and the start of their 2014 FIFA World Cup qualifying campaign.