The Americans will play Scotland in Jacksonville, Florida, and four days later face Brazil in suburban Washington. Four days after that match, they face Canada in Toronto.
Those matches will set the stage for the first CONCACAF semi-final group stage match for the Americans against the Caribbean dual-island nation on 8 June in Tampa, Florida. Antigua and Barbuda have never faced the Americans.
Jamaica and Guatemala are also in the group and only two teams will advance to next year's final round of qualifying for the 2014 FIFA World Cup in Brazil. "Our focus since last summer has been to prepare this team for World Cup qualifying," US coach Jurgen Klinsmann said. "It's critical that we start qualifying off on the right foot."
The Americans are 1-3 with two drawn against Scotland in a rivalry dating to 1949. They last met in 1998, a 0-0 draw in the Americans' final FIFA World Cup warm-up match.
Click on the links to the right to read FIFA.com's recent two-part interview with Jurgen Klinsmann.