Germany midfielder Marco Reus is out of Friday's friendly against Ukraine in Kiev because of intestinal flu, the fifth time the rising Borussia Monchengladbach star has had to withdraw for his country.
The 22-year-old has been in stellar form for Gladbach this season with seven goals in 12 league games, but illness meant he could not join up with the Germany squad today.
It remains to be seen whether he will be fit for next Tuesday's friendly against the Netherlands in Hamburg, when he could win his third cap having made appearances off the bench against Turkey and Belgium last month.
"According to his condition from Monday afternoon to Tuesday morning, it is not feasible for him to travel due to health reasons," said the German Football Federation (DFB) in a statement.
He is the second German to drop out of Friday's match at Kiev's Olympic Stadium after veteran striker Miroslav Klose withdrew yesterday with a knee injury.
Reus has a long history of leaving Germany squads, starting back in May 2010 when he missed the friendly win over Malta with a bruised leg.
Then a groin injury in September kept him out of the final qualifier victory over Austria and the 2-2 friendly draw with Poland in Gdansk.