Midfielder Winston Kalengo scored after 30 minutes to give the home side their first win and inflict a first loss on Sfaxien.
Sfaxien lead Zanaco on goal difference in Group B with each club having accumulated four points from three matches, although the Tunisians have played at home only once while the Zambians have done so twice.
Surprise last-eight qualifiers FUS Rabat of Morocco, whose victims included title holders Stade Malien of Mali, host Harras al-Hodoud of Egypt late tomorrow and a win for either would take them to the top of the table.
Al-Hilal of Sudan maintained the sole 100 per cent record among the eight challengers for a $660,000first prize with a 2-1 victory over Malian visitors Djoliba yesterday.
Milutin Sredojevic's side stormed into a two-goal lead within 31 minutes through Mudathir Eltaib and Mohamed Bashir. But after weathering repeated second half pressure, Djoliba pulled a goal back in stoppage time when Ousmane Cisse struck.
Hilal, seeking a first African title after twice finishing CAF Champions League runners-up, have nine points, Al-Ittihad of Libya three and ASFAN of Niger and Djoliba one apiece.
Ittihad host ASFAN, another surprise qualifier after ousting multi-African title winners Etoile Sahel of Tunisia during the knockout stage, tomorrow.