Inter Milan have drawn their last three league games to allow AC Milan and Roma back into the Serie A title race. Roma boss Claudio Ranieri insists, however, the only way Inter will not win a fifth straight Serie A title is if they "give it away".
"Inter are of a different planet," said Ranieri. "Only they can lose the scudetto. We just have to remain calm and point towards finishing in the top three positions."
Roma head into Sunday's match at Napoli on the back of seven consecutive league triumphs but knowing they will be tested by a side who have yet to lose at the San Paolo this season. Milan, meanwhile, host relegation-threatened Atalanta.
They go into the clash on the back of a 2-1 win at Fiorentina in midweek that allowed them to leapfrog Roma into second place and pull to within four points of Inter. "We are only thinking about ourselves," said Milan boss Leonardo. "Of course we can keep dreaming but we have to remain calm and maintain our quality of play."
Inter play at Udinese and they head into the encounter feeling very confident after a 2-1 win over Chelsea in the first leg of their UEFA Champions League tie. Coach Jose Mourinho serves the first part of a three-match touchline ban, while defenders Ivan Cordoba and Walter Samuel are also suspended and will not play.
Fourth-place Juventus will be looking to make it three wins in a row when they face sixth-placed Palermo on Sunday. Juve are just one point clear of Napoli, Palermo and Sampdoria. Samp will hit the road and play at Parma.
Ninth-place Genoa will try to take another step towards European qualification with a win against Bologna. I Grifoni lie two points behind Palermo and have reason to be optimistic after just one home defeat this season, a 5-0 thrashing by Inter on October 17.
Lazio and Fiorentina will battle it out at Rome's Stadio Olimpico on Saturday with both teams looking to spark their season into life. Both sides go into the encounter on the back of defeats, with Lazio falling at Palermo last week and the Viola having slipped up against Milan.
Cagliari will be desperate to bounce back from their bitter defeat to Udinese in midweek with a triumph over Chievo in Verona. The Sardinian outfit missed a chance to climb to fourth after allowing the Friuli outfit to come from behind and claim a 2-1 win on Wednesday.
A win at Catania could see Bari take a giant step towards securing their Serie A status for another year. The promoted outfit have collected 32 points in 25 games and are already nine points clear of the drop zone.
Livorno are in the relegation zone and they play at home against bottom-placed Siena on Sunday. Gli Amaranto are 18th, one point behind Catania, who hold the last safe position.