Ryota Moriwaki nodded home a decider in stoppage time to give Sanfrecce Hiroshima a 2-1 win over Nagoya Grampus and maintain their two-point lead in the J.League.
Sanfrecce have now 50 points, ahead of Vegalta Sendai on 48 points, Urawa Red Diamonds on 45 points, and Jubilo Iwata on 42 points.
Vegalta defeated Vissel Kobe 2-1, with Shingo Akamine scoring an equaliser in the 42nd minute and Jiro Kamata hitting home a decider in the 90th minute.
Urawa crashed to a humiliating 5-0 defeat by Gamba Osaka, their worst since they lost to the same team 6-1 in 2008.
"It was a very bad game for us. We couldn't do what we have to do for the first time this season. I must accept that it was my responsibility," said Urawa coach Mihailo Petrovic.
Jubilo were held to a goalless draw by Albirex Niigata. In other games, Consadole Sapporo were on the verge of returning to the second division after losing to Omiya Ardija 5-0, while Yokohama F Marinos defeated seven-time champions Kashima Antlers 2-1.
Cerezo Osaka defeated Shimizu S-Pulse 3-2, Kawasaki Frontale downed FC Tokyo 2-1, and Sagan Tosu outclassed defending champions Kashiwa Reysol 3-1.