Germany's Brazil-born forward Cacau warmed-up for Wednesday's friendly against the South Americans with a goal in a 3-0 victory for 2007 German champions VfB Stuttgart over Schalke.
Title holders Borussia Dortmund had started proceedings with an impressive 3-1 win over Hamburg on Friday thanks to two goals from Germany's rising stars Kevin Grosskreutz and Mario Goetze.
But Stuttgart also picked up three points and Cacau, who will be back at Stuttgart's Mercedes Benz Arena on Wednesday when Germany face Brazil, opened the scoring with a 37th-minute header. The hosts added a second against last season's UEFA Champions League semi-finalists when Austrian striker Martin Harnik scored with a 56th-minute header.
Striker Shinji Okazaki, who has been named in the Japan squad to face South Korea on Wednesday, made sure of the three points with a superb strike on 89 minutes to make his side joint early league leaders.
"It's nice that we could contribute to this festival of football," Stuttgart coach Bruno Labbadia said. "We restricted them and created lots of chances."
Hannover 96, who face Sevilla in a UEFA Europa League play-off on 18 August, were also winners with a 2-1 victory over Hoffenheim.
Ex-Germany striker Jan Schlaudraff put Hannover ahead when he slotted home a free-kick on 15 minutes, only for Hoffenheim to equalise three minutes later when midfielder Sejad Salihovic converted a penalty.
When Schlaudraff was fouled in the area on 30 minutes, Norwegian striker Mohammed Abdellaoue stepped up to secure all three points for Hannover.
Having spent last season flirting with relegation, Werder Bremen got their season off to a flying start with a 2-0 home win over Kaiserslautern as Swedish striker Markus Rosenberg scored twice in the second half.
Patrick Helmes scored twice as 2009 champions Wolfsburg won 2-0 at Cologne as coach Felix Magath named midfielder Christian Traesch as skipper after stripping Marcel Schaefer of the captaincy. Schaefer had the final say as his late header sealed the three points before Helmes scored his second in added time.
Striker Sascha Moelders scored with two headers as newly-promoted Augsburg earned a 2-2 draw at home to Freiburg.
Hertha Berlin, back in the Bundesliga after winning the second division last season, were beaten 1-0 at Berlin's Olympic Stadium after Nuremberg's 22-year-old Czech Republic striker Tomas Pekhart netted the winner.
Bayern Munich open their season on Sunday at home to Borussia Moenchengladbach while Bayer Leverkusen are at Mainz.