Paris Saint-Germain sporting director Leonardo resigned on Wednesday, the club announced in a statement.
"The club management regrets this decision, but respects it," the statement said, adding that the resignation would take effect from September 2.
"The club would like to take the opportunity to thank him for the remarkable work he put in to build in Paris a team that is now in the forefront of European football and wishes him every success in his brilliant career."
The former AC Milan and Inter Milan coach was named as sporting director at the Paris club in July 2011 after they were taken over by investors from the Gulf state of Qatar.
He attracted top names such as Zlatan Ibrahimovic, Thiago Silva and David Beckham to the Parc des Princes. After Carlo Ancelotti departed for Real Madrid, he helped bring in former France national team coach Laurent Blanc to be in charge for the 2013/14 season.