Jose Mourinho's Chelsea face Tottenham at Stamford Bridge on Saturday and the Blues manager believes victory will help them achieve their first target of the campaign.
Mourinho's side are the only one of the top four in league action this weekend and a win will move the leaders seven points clear of Arsenal and Liverpool and nine points ahead of Manchester City, who will have three games in hand on the Stamford Bridge club.
A win for Chelsea will also move them 13 points ahead of Tottenham in fifth, with nine games remaining.
Mourinho again refused to install his side as title favourites but conceded a win would all but guarantee a top four finish and a route into next season's UEFA Champions League.
"We want our top four position safe and, in this moment, the biggest threat for that top four position is Tottenham because they are fifth and the closest team to the top four," he said.
"If we can get a result against them, we can say that, almost for sure, our objective of finishing top four is in a very good direction."
And referring to Chelsea's position in relation to their main rivals, he added: "I keep saying that is not a realistic situation.
"When teams have played the same number of matches you can say properly if you're in front or behind.
"When some teams have played more matches than others, the situation is not real. I don't look at the table, I look at the game."
Mourinho also revealed Ashley Cole would be out for up to ten days after damaging a knee ligament in training.
The left-back made the most of a rare starting opportunity to press his claims for a place in England's FIFA World Cup™ squad in the midweek friendly win over Denmark.
But Mourinho said: "Unfortunately he got an injury yesterday in training and is one of the players who is out tomorrow.
"A lateral ligament, a little thing, but impossible for tomorrow and between eight and ten days."