Manchester City striker Mario Balotelli has lost his appeal against a three-game ban after being sent-off against West Bromwich Albion in the Premier League last weekend.
The Football Association upheld Tuesday the straight red card Balotelli, who scored both goals in a 2-0 win, received for violent conduct following a clash with Youssouf Mulumbu.
An FA statement said: "At a Regulatory Commission hearing today, a claim that the standard punishment is clearly excessive from Manchester City's Mario Balotelli was dismissed.
"As a result, Balotelli will serve a three-match suspension with immediate effect."
The decision means the 20-year-old Italy forward will miss not only Wednesday's Manchester derby but also the visit of Birmingham and City's subsequent trip to Fulham.