Bayern Munich, Real Madrid, Inter Milan, Manchester United and Lyon all underlined their title credentials at the weekend with important early-season victories. However, rivals Chelsea, Manchester City, Juventus and Bordeaux remained firmly on the pace.
FIFA.com reviews the weekend action from around Europe's leading leagues.
Bundesliga: Bayern bounce back
Germany's most successful club Bayern Munich are back to winning ways. After a poor opening to the campaign, in which Louis van Gaal's men failed to win any of their first three games, the Bavarians finally chalked up a first victory - and it came in emphatic style against champions Wolfsburg. New signing Arjen Robben struck twice on a scintillating debut as Bayern beat the Wolves 3-0.
Top spot in the standings is shared by Hamburg, 3-1 winners against Cologne, and Bayer Leverkusen, who beat Bochum 2-1 at home. Bayer's match-winner was again Stefan Kiessling, who fired his fourth goal in as many games. Schalke suffered a first real setback of the new term with a 1-0 home defeat to promoted Freiburg. Werder Bremen climbed to third with a 3-2 success away to struggling Hertha Berlin.
Top three: Hamburg, Bayer Leverkusen (both 10 points), Werder Bremen (7)
Bottom three: Hertha Berlin (3), Nuremberg (2), Cologne (1)
Leading scorers: Paulo Guerrero, Stefan Kiessling (both 4 goals), Ioannis Amanatidis, Eren Derdiyok, Jiri Staijner, Mesut Ozil (all 3)
Weekend stat: 4 - Werder Bremen won a fourth competitive match on the bounce to move within touching distance of the top.
Premier League: Chelsea and Tottenham march on
Spurs and the Pensioners are the top dogs in England at present. Chelsea brushed aside promoted Burnley 3-0 to maintain their perfect start with four wins in four matches, a feat emulated by London rivals Tottenham, although the men in white needed an injury-time winner to beat Birmingham City 2-1.
In the big match of the Premier League weekend, Manchester United came from behind to register a fortunate win over Arsenal. Andrei Arshavin handed the Gunners a half-time lead, but Wayne Rooney converted a penalty and Abou Diaby unluckily put through his own goal as the Red Devils sneaked the points. Big spending Manchester City also maintained their 100 per cent record, albeit after three rather than four games, with a workmanlike 1-0 success away to Portsmouth.
Top three: Chelsea, Tottenham Hotspur (both 12 points), Manchester United (9)
Bottom three: Blackburn Rovers (1 point), Bolton Wanderers, Portsmouth (both no points)
Leading scorers: Jermain Defoe, Wayne Rooney (both 4 goals), Emmanuel Adebayor, Didier Drogba, Fernando Torres (all on 3)
Weekend stat: 3 - In his third appearance for his new club, Togo goal-getter Adebayor scored his third goal to hand Manchester City a third win in their third fixture.
Ligue 1: Trio set the pace
Bordeaux, Paris St Germain and Lyon share the lead at the top of Ligue 1. Champions Bordeaux were held to a goalless draw away to fifth-placed Marseille, while the men from the capital beat Lille 3-0, and Lyon saw off Nancy 3-1.
The mantle of surprise package goes to promoted and as yet undefeated Montpellier, who won away to Nice and lie fourth.
Top three: Bordeaux, Paris St Germain, Lyon (all 10 points)
Bottom three: Lille, Auxerre (both 1 point), Grenoble (no points)
Leading scorers: Yoann Gourcuff (4 goals), Marouane Chamakh (3)
Weekend stat: 6 - The number of teams still undefeated after four matches. The clubs in question are the top five plus Stade Rennes.
La Liga: Getafe and Malaga quick off the blocks
Getafe and Malaga were the big winners on Matchday 1 in Spain. Getafe travelled to face Racing Santander and won 4-1, while Malaga impressively saw off Atletico Madrid 3-0.
Real Madrid's expensively-assembled side scraped a 3-2 home win over Deportivo La Coruna. Raul, Cristiano Ronaldo (penalty) and Lassana Diarra hit the target for the perennial title contenders.
Top three: Getafe, Malaga, Mallorca (all 3 points)
Bottom three: Xerez, Racing, Atletico Madrid (all no points)
Leading scorers: Roberto Soldado (3 goals)
Weekend stat: 1 - For the first time in his long and eventful career, Real Madrid striker Raul scored the first La Liga goal of the season.
Serie A: Inter embarrass Milan
The Milan derby took pride of place in the Italian schedule. Champions Inter underlined their role as favourites to retain the Scudetto with a thoroughly convincing 4-0 demolition job on city rivals AC Milan. Jose Mourinho and his men already look the team to beat in Italy this term.
Juventus appear the best bet to run Inter close after a 3-1 victory away to Roma, newcomer Diego firing a brace and Felipe Melo completing the scoring. Sampdoria are top of the nascent standings after a 3-1 victory against Udinese. Genoa won 1-0 away to Atalanta and Lazio beat Chievo Verona 2-1 to maintain 100 percent records after two games.
Top three: Sampdoria, Juventus, Genoa (all 6 points)
Bottom three: Chievo Verona, Atalanta, Roma (all on no points)
Leading scorers: Antonio di Natale (3 goals), Diego, Pato (both 2)
Weekend stat: 35 - The number of years since Inter recorded as big an "away" win over bitter rivals AC. The score 35 years ago was 5-1 to the Nerazzurri.
Russian champions and current leaders Rubin Kazan ran up a psychologically important 3-0 victory away to pursuing Spartak Moscow, and are now four points clear at the top of the Premier Liga.
Anderlecht remain top in Belgium. The Brussels outfit drew 1-1 with champions Standard Liege in a first re-run of last term's title play-off and retain top spot.