San Lorenzo took the lead in the 20th minute thanks to a Mauro Matos goal following a long run by Angel Correa. However, the home team missed a number of opportunities and Gustavo Canales netted the equaliser in the 83rd minute that led to boos from the home support at the Estadio Pedro Bidegain. San Lorenzo share the lead in Group Two on four points with Independiente del Valle and Botafogo.
Independiente beat nine-man 2-1 at home thanks to a last-gasp goal by Junior Sornoza in stoppage time. Christian Nunez had put Independiente ahead in the first period before Bolivar levelled in the 59th. During the second half, both Bolivar and Edilson were sent off and Botafogo played the last 21 minutes two men down.
Libertadores champions Atletico Mineiro gained a point from their trip to Paraguay as they drew 2-2 with hosts Nacional. Paulo Cesar's side fell behind to Marcos Melgarejo's effort in the ninth minute after Julian Benitez's pass, but Ronaldinho assisted Josue and he beat keeper Ignacio Don to equalise in the 22nd. Jo made it 2-1 four minutes later, but Silvio Torales netted a penalty and levelled the duel three minutes from time
Atletico Mineiro top Group Four on 7 points, three above Nacional, while Venezuela's Zamora defeated Santa Fe 2-1 to go level with the Colombian side on three points. Pedro Ramirez put Zamora ahead with a 58th-minute penalty and Jonathan Copete equalised in the 71st, but Juan Falcon netted the winner with seven minutes remaining in Barinas.
Finally in Rio de Janeiro, Bolivar of Bolivia were very close to making history by winning at the Maracana, but came away with a 2-2 draw against Flamengo. Everton netted a brace for Flamengo while Jose Capdevilla and Ricardo Pedriel scored for the visitors who remain at the bottom of Group Seven. Flamengo remain second on four points, two below leaders Emelec of Ecuador.