Uruguayan giants Penarol earned a tough point from their trip to Venezuela as they drew 1-1 with Deportivo Anzoategui in Copa Libertadores Group Eight.
The five-time Libertadores champions were far from their best and were a goal down until the 78th minute, when veteran striker Marcelo Zalayeta levelled.
Framber Villegas had put Anzoategui ahead in the 38th minute and his team did their best to withstand the pressure from Penarol in Puerto La Cruz city. However, Jonathan Rodriguez passed to Zalayeta, who dispatched clinically past keeper Edixon Gonzalez.
Penarol coach Jorge Fossati said: "We corrected some things at the interval and improved a lot in the second half. (Goalkeeper Juan) Castillo was a spectator as Anzoategui carried no threat."
There was no luck for Brazilian teams Flamengo and Cruzeiro, who both suffered away defeats.
Flamengo were beaten by Mexican side Leon in Group Seven, with Argentinian striker Mauro Boselli starring. Boselli netted a 31st-minute penalty to put Leon ahead but then missed another spot-kick.
Victor Caceres equalised for the Brazilian side two minutes before the end of the first period, but Franco Arizala gave Leon the win at the midway point of the second half.
"I think this is a good first step. Even though we missed some opportunities, the important point is the team having opportunities to score. We will take confidence from this victory," Leon coach Gustavo Matosas commented.
Cruzeiro, meanwhile, let a lead slip as Peruvian side Real Garcilaso came back to win 2-1.
Bruno Rodrigo netted for Cruzeiro in the 19th minute, but Ezequiel Britez levelled six minutes after the break. In the 61st minute, Ramon Rodriguez del Solar handed the victory to Freddy Garcia's side in Group Five.
Finally in Group Three, in Colombia, Cali claimed a 1-0 win over Paraguayan side Cerro Porteno with a 72nd-minute header from Jhon Viafara.