Internacional came from a goal down to secure a 2-1 away win over Mexican giants Guadalajara in the first leg of the Copa Libertadores final.
Guadalajara took the lead on the stroke of half-time against the run of play through a neat header from Mexico international Adolfo Bautista. It was an undeserved lead for the hosts, with Inter having the better of the first-half chances and hitting the post twice through Kleber and Alecsandro.
But the Brazilian side, who won the title in 2006, turned the match on its head after the interval. Giuliano equalised with another header in the 72nd minute to silence the home fans at the new Omnilife stadium, and four minutes later Bolivar gave Celso Roth's side the lead from an Andres D'Alessandro cross that Indio Antonio de Lima sent back into the box.
The result ensured Inter will head into next Wednesday's sell-out return match knowing they will be crowned champions if they avoid defeat in Porto Alegre.
Giuliano commented: "I'm happy to be blessed with this goal, but I'm even happier because of the way the team played this match. It was amazing."
Internacional went into the match having already secured qualification for the 2010 FIFA Club World Cup in Abu Dhabi.