The German giants meet Chelsea in the final at their Allianz Arena stadium on Saturday. The Blues booked their place in the final following a magnificent defensive display when down to ten men against Barcelona at the Camp Nou, but Neuer expects them to adopt a more attack-minded approach in Munich.
"Chelsea are tactically very well schooled and they showed that in both games against Barcelona," the Germany international said. "I don't think they are going to be as defensive against us as they were against Barcelona. That is not to say they will go all out attack, but they will probably play a controlled attacking style."
Neuer feels keeping 34-year-old Drogba, who caused the Catalans plenty of problems, quiet will be key for a Bayern side missing centre-back Holger Badstuber and left-back David Alaba, as well as holding midfielder Luiz Gustavo, through suspension.
"He is a very good striker and has a strong physical presence and he knows how to put himself about," the former Schalke goalkeeper said. "We have seen this season in the Champions League how dangerous he is."
At the other end of the pitch Mario Gomez will be tasked with getting Bayern's goals, but the striker admits the Premier League side will be tough to break down. "We know they are a very strong team with lots of experience and players who have been around at the highest level for up to 15 years. They are in the final because they deserve to be here."
'Special atmosphere' in Munich
Bayern, beaten in the final by Jose Mourinho's Inter Milan in Madrid two years ago, will be the first side to play in a Champions League final in their own stadium and Gomez claims the city is buzzing ahead of the showdown.
"This is the only thing people are talking about," he said. "The anticipation is huge. We are beginning to realise now how big this is, having the Champions League final in our own city. There is a special atmosphere and everybody in the club is looking forward to this game."
Saturday is the last chance for Bayern to win silverware this season after Borussia Dortmund beat them to the Bundesliga title and the DFB-Pokal. And Neuer believes it is important they make the most of their home advantage.
"We are not putting ourselves under too much pressure because it is a home game, we have got to use that to our advantage," he said. "We have the same hotel as before any other home game, we have our own dressing room, we have all we need to feel good and we have got to make the most of that.
"Then we have the fans behind us. We have got to take advantage of this. We can't wait for it, it is the highlight of the season and we know that it is getting closer. This is the biggest title you can win in club football.
"This is the biggest highlight of my career so far and, in club football, this is the greatest. We deserve to be in the final. We know that it is our biggest game, and a home game with people behind us, and the signs are good for us. Everybody wants to get their hands on this trophy."