Reigning Argentinian champions Estudiantes came back from a goal down to beat Guarani 2-1 in Paraguay in the Copa Libertadores.
A 44th-minute penalty goal by Pablo Caballero gave Guarani the lead but Estudiantes needed only eight minutes in the second half to turn the Group 7 match around. Pablo Barrientos was assisted by Raul Iberbia before netting in the 50th minute - and three minutes later Leandro Gonzalez shot home from outside the box to set up the victory for Eduardo Berizzo's team.
Estudiantes defender Gabriel Mercado said afterwards: "It was a very important match for us and this is a great victory. We managed to recover from the 5-0 defeat to Cruzeiro in the first matchday and two wins in a row means recovery is closer. Our first half form was very poor, but we managed to change our mind then."
In Santiago, Venezuelan giants Caracas claimed a surprise 3-1 win in their trip to Chilean giants Universidad Catolica to take the lead in Group 4. Four minutes were lethal for Catolica, as Luis Cabezas opened the scoring seconds after the half-time break before Nelson Barahona doubled the gap at the 48th.
In the 50th minute, Cabezas headed the ball into the back of the net to make it 3-0, before Pablo Calandria reduced the deficit three minutes later. Catolica defender Hans Martinez was dismissed in the 69th minute after fouling Edgar Jimenez.
Colombian side Junior remain unbeaten in Group 2 following a 2-1 away win over Oriente Petrolero in Bolivia. Victor Cortes put Junior ahead in the 27th minute and Luis Paez widened the gap two minutes into the second half, before Juan Carlos Arce replied for Oriente at the end.
A second half goal by Luis Aguiar gave Uruguayan giants Penarol a 1-0 triumph over Ecuador's Liga de Quito in Montevideo. Aguiar's goal in the 57th minute put Penarol on top of Group 8 with six points, three more than Liga and Argentinian duo Independiente and Godoy Cruz.